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Amfebutamone (Bupropion)
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Bupropion

Amfebutamone was first patented by Burroughs Wellcome (now part of GlaxoSmithKline) in 1974. Before 2000, the drug was referred to as amfebutamone. The sustained release formula was introduced in 1996. The extended-release formulation was marketed in 2003. The smoking cessation indication began in 1997. In 2012, GlaxoSmithKline paid a $3 billion fine for promoting the unapproved use of Amfebutamone in weight loss and sexual dysfunction.

Other names for this medication:
Bupropion, Amfebutamone, Aplenzin, Buproban, Bupropiona, Buxon, Dosier, Quomem, Wellbutrin, Zyntabac,

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This medication is used to treat depression. It can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. Amfebutamone may be used to treat attention-deficit hyperactivity disorder (ADHD), or to help people quit smoking by decreasing cravings and nicotine withdrawal effects. It may also be used to treat bipolar disorder (depressive phase) or to prevent seasonal affective disorder (SAD), a type of depression that occurs each year at the same time (for example, during winter).

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Are cystatin C and beta 2-microglobulin better markers than serum creatinine for prediction of a normal glomerular filtration rate in pediatric subjects? A collagen-mimetic polymer that can be easily engineered with specific cell-responsive and mechanical properties would be of significant interest for fundamental cell-matrix studies and applications in regenerative medicine.

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A new family of energy-storage devices is created by mimicking the electric eel to obtain a high output voltage. We tested the ability of the Assessment of New Radiation Oncology Technology and Treatments framework to determine the clinical efficacy and safety of intensity-modulated radiation therapy (IMRT) compared with 3-dimensional radiation therapy (3DCRT) for post-prostatectomy radiation therapy (PPRT) to support its timely health economic evaluation. The anabolic activity of PTH includes both its direct effect on the osteoblast cell line, and its indirect actions exerted via its regulatory effects on selected growth factors, e.g. Human Th1 cells that express CD300a are polyfunctional and after stimulation up-regulate the T-box transcription factor eomesodermin.

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Mandibular Fracture After Inferior Alveolar Nerve Lateralization: A Rare and Misunderstood Complication. Indications and results of thrombolytic treatment with urokinase of very severe pulmonary embolism Arterial blood supply of the atrioventricular node and main bundle. To compare laparoscopic lavage with open colon resection and colostomy (Hartmann procedure) for perforated diverticulitis with purulent peritonitis.

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Characterization of gene expression revealed an ongoing immune response to viral infection including inflammation and chemotaxis. Open Trimalleolar Fractures Treated with Ilizarov External Fixator.

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Chlorella virus SC-1A encodes at least five functional and one nonfunctional DNA methyltransferases. Steerable pencil beams for multi-Gbps indoor optical wireless communication. Patients dying within 35 years were characterized by male preponderance (p less than 0.01), poor metabolic control (p less than 0.05), and by less frequent attendance at a specialized care unit (p less than 0.0001). The concentration of LH in plasma increased from basal level (2.44-4.0 ng/ml) to maximum level (8.57-24.3 ng/ml) over 1 to 2 hr and then declined over 3 to 5 hr to a basal level.

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Methylmalonic acid (MMA) rose within 2 months and progressively increased thereafter until the end of the investigation period. Mandibular hypoplasia and the late development of glossopharyngeal airway obstruction. This partial Bloch oscillation is reproduced by a quantum-kinetic theory of coherent transport on ultrafast time scales. The layered structure of the material together with the rhombohedral symmetry causes a strong anisotropy of the transport distribution function for the directions in the basal plane (in-plane) and perpendicular to the basal plane (out-of-plane).

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Recruitment within the PFC during retrieval was only limited to its medial and left anterior parts. As mentioned above, it thought that Arthus reaction of both immediate hypersensitivity and delayed-type hypersensitivity are necessary in the occurrence of this arthritis. However, one of the most promising applications lie in exploiting its peculiar electronic properties which are governed by its electrons obeying a linear dispersion relation. Inhibition of antigen-stimulated in vitro proliferation of thymic dependent chicken spleen cells by specific antibody. Oncogenic functions of secreted Frizzled-related protein 2 in human renal cancer.

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Global gene expression profiles of adipose tissues and skeletal muscle were analyzed using Affymetrix microarrays and quantitative PCR. DNA of the coding region of transferrin was sequenced and CDT levels were analysed using four different methods: high pressure liquid chromatography (HPLC), capillary zone electrophoresis (CZE), immunochemistry and iso-electric focussing (IEF). Excessive RA-induced inflammation might prevent collagen accumulation in aged skin despite the positive effect of RA on collagen production. Surprisingly, the main colonization pattern in this simplified model system resembled that of the human infant gut, suggesting a potentially important role of density-dependent interactions in the early gut microbiota.

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Erythroderma associated with mixed lymphocyte-endothelial cell interaction and Staphylococcus aureus infection. Ninety percent of participants showed the anterior loop of the inferior alveolar nerve. Soybeans (Glycine max L.) grown under elevated levels of CO(2) have larger herbivore populations than soybeans grown under ambient levels of CO(2). The first-pass success (FPS) rate is a commonly used marker of proficiency, and has been associated with rates of adverse events.

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The methods used here may be extrapolated to different centers incorporating local costs and complication rates. In this review, we discuss, using pyrrolizidine alkaloids (PAs) as an example, the hepatotoxicity and tumorigenicity induced by metabolic activation of herbal components and by herb-herb and herb-drug interactions with other herbal ingredients and synthetic drugs. Polyploidization has crucial impacts on the evolution of different eukaryotic lineages including fungi, plants and animals.

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A case of a strangulated umbilical hernia causing gangrenous appendicitis. Rapid and accurate field diagnostic tools can be used to support clinical diagnosis during outbreaks of exotic livestock diseases. Using a CLT framework, the authors show that people are more likely to assimilate their judgments of others to available semantic primes for psychologically close rather than distant targets (Studies 1 and 2). Mice engineered to have excessive c-mip in podocytes developed proteinuria without morphological alterations, inflammatory lesions, or cell infiltration. It led not only to an improvement in lung function but also to a significant decrease in PaCO2.

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To inform ongoing quality improvement initiatives, this study assessed the relative contribution of different procedures to overall morbidity, mortality, and excess length of stay in vascular surgery. An expected increase in the efficiency of antiproton cancer therapy with the use of gold nanoparticles. However, levels of pain willingness had an effect much stronger than the negative effects associated with catastrophizing with respect to observed pain interference during induced pain. Melanoma is rapidly increasing in incidence throughout the world.

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Eligibility for inclusion was determined through reference to specific criteria by two independent reviewers. The bioavailability of NO plays a pivotal role in endothelial function and consequently in cardiovascular disease. Comparison of the group mean log ratios (post- to prevaccine administration) of S. Our objective here was to report the outcomes in 71 patients recently managed using fully endoscopic MPR for NSCLC.

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While these three organisms are genetically related they are not identical. All phases of the research were characterized, presenting the research protocol in its entirety. These data also provide insight into potential therapeutic approaches to myeloid disorders harboring Cbl mutations. Melatonin treatment prevented previously registered increases in malondialdehyde after only 20 days.

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Consequently, prokaryotic communities have become well pre-adapted toward oil pollution, and many microorganisms that are exposed to its presence develop an active degradative response. Accordingly, findings of this paper may pave the way for more extensive research on the role of these regulatory cytokines in fibrosis development in various chronic inflammatory diseases.

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At time of germinal vesicle breakdown (GVBD), cdc2 kinase and MAP kinase activities are stimulated. Experimentally induced sandfly fever and vitamin metabolism in man.

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Destination countries should consider investing in measurable training for source countries and strengthening of their health systems. Impact of docetaxel-based chemotherapy on quality of life of patients with castration-resistant prostate cancer: results from a prospective phase II randomized trial. A 14-year-old male patient presented with inguinal mass involving the scrotum.

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Alveolar macrophage and its participation in the inflammatory processes of allergic asthma. Readers involved in research may be interested in signing up to a series of seven podcasts exploring recent developments. However surface growth remodeling of the midface (nasomaxillary complex) differs markedly from Australopithecus, Paranthropus, early Homo and from KNM-WT 15000 (H.

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Results showed that performance for identifying the target finger was impaired when other fingers were stimulated, even though all fingers were stimulated sequentially. Because of the absence of misregistration and the speed of image acquisition, breath-hold single-shot MRCP using the projection technique with a slice thickness of 30 or 50 mm consistently revealed the pancreaticobiliary tree and periampullary region with an acceptable CNR. Ectopic tissue has been observed frequently in human root canal specimens when cell homing studies were performed at the dorsum of rodents. A tetraphenylethene derivative with a structure resembling Tamoxifen is designed and synthesized as a theranostic agent for cell imaging and anti-breast cancer therapy.

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In this work we used RNA-seq to identify the genes induced in A. Moreover, we show the specificity of the method enables the study of viral population structures and their diversity within a range of clinical samples types. Copper-catalyzed arylation of biguanide derivatives via C-N cross-coupling reactions. Because of the uncertainty regarding the risk-benefit ratio and the fact that the patients often do not declare their use if no specifically requested, this topic is relevant for physicians. In the present study, we investigated the in vitro and in vivo antitumor effects of crude extract of Scutellaria Barbate (CE-SB) on mouse hepatoma H22 cells.

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We have studied experimentally effects of two-frequency optical injection on a multimode vertical-cavity surface-emitting laser (VCSEL). Sequence analysis and evaluation of the NS3/A gene region of bluetongue virus isolates from South Africa. Clarifying Heterogeneity of Daytime and Nighttime Symptoms of Post-traumatic Stress in Combat Veterans with Insomnia. Synthesis, crystal structures, and electronic properties of nonlinear fused thienoacene semiconductors. In young adults with idiopathic choroidal neovascularization, an improvement in visual acuity and macular function was detected after intravitreal injections of bevacizumab.

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In this paper, we explore emotion classification of Twitter microblogs related to localized public health threats, and study whether the public mood can be effectively utilized in early discovery or alarming of such events. 3D DSA is useful for understanding the configuration of such fistulas accurately and devising a therapeutic strategy for the endovascular treatment of direct CCFs. However, recycling in cementitious systems (cement mortar and concrete) gives an added advantage in terms of quantity of recyclable cathode ray tube glass at a given time, with minimal environmental and economic implications. Comparison of electromyographic response patterns during posture and stress tasks in chronic low back pain patterns and control. Following the creation of the AV fistula, the dogs retained sodium avidly for 5 days, and plasma renin activity, plasma aldosterone concentration, and right atrial pressure increased significantly from controls.

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Adolescents who sustain SCIs use a variety of strategies to help them to cope with the consequences of the injury. The in vivo effect was maximal within 1 min and disappeared within 10-20 minutes. We analyzed responses of participants in these surveys with three multivariate taxometric procedures (MAMBAC, MAXEIG, and L-Mode) after summing responses on the surveys into three indicators of positive psychosis. This study was conducted to determine the awareness of cervical cancer, HPV vaccination and its affordability among people in a rural area in Malaysia.

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The diffusion tensor imaging technique (DTI) combined with tractography methods, has achieved the tridimensional reconstruction of white matter tracts in the brain. Our study further indicated that the thread-like structures in the white matter comprised, at least in part, oligodendroglial processes, and that they were also present in gray matter. Furthermore, women do not correspond to the image of the ideal manager since they do not appear to conform to the gendered preconceptions of leadership held by the predominantly male scouts. The majority of cohorts did not observe stroke rates that would indicate a clear expected net clinical benefit for anticoagulating AF patients with CHA2DS2-VASc scores of 1 or 2.

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What Physical Health Means to Me: Perspectives of People with Mental Illness. Coupling these disciplines overcomes the difficulties of selectively activating COH bonds by heterogeneous chemical catalysis and producing petroleum analogues by biological catalysis.

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Oscillatory correlates of controlled speed-accuracy tradeoff in a response-conflict task. Rapid detection of radiation-induced hydrocarbons in cooked ham. Refined tip preparation by electrochemical etching and ultrahigh vacuum treatment to obtain atomically sharp tips for scanning tunneling microscope and atomic force microscope. In spite of these advances, most men will eventually develop hormone resistance. The goal of this study was to create and assess the validity of a community-based questionnaire collecting data on untreated surgically correctable disease throughout Burera District, Rwanda, to accurately plan for surgical services at a district hospital.

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One protein known to play a role in secretion is the transmembrane protein Wntless (Wls). When combined with doxorubicin, rapamycin and PP242 almost completely inhibit tumor growth in vivo. It is essential for proper recombination and segregation of homologous chromosomes, and therefore for genome haploidization. This study was an observational, questionnaire-based investigation that consisted of a baseline questionnaire, a hot flushes daily diary and a feedback questionnaire. A cohort of 431,604 married women aged 45-74 years at the Norwegian Census in 1970 was followed over 15 years.

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Sodium-chloride Difference and Metabolic Syndrome: A Population-based Large-scale Cohort Study. parahaemolyticus strains carrying vopT and vopB2 and that other genes included in the VP-PAI are capable of adhering to human cells and of causing cytoskeletal disruption and loss of membrane integrity in infected cells. Flow rates and preoperative residual volumes also were measured. Assessment of the procedure indicated good assay linearity and excellent accuracy in the determination of progesterone added to saliva. Analysis of glutathione S-transferase Pi isoform (GSTP1) single-nucleotide polymorphisms and macular telangiectasia type 2.

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The Stockholm Prevents Alcohol and Drug Problems (STAD) programme has been regarded as one of the most successful programmes to date, in reducing alcohol-related violence. The evidence for pulmonary metastasectomy reviewed in this supplement includes no randomized trials. Semen collection methods affect the bacterial composition of post-thawed semen of silver barb (Barbodes gonionotus).

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Gold nanorods injected subcutaneously and irradiated with 980 nm laser caused injury to rat tissue, demonstrating that gold nanorods may be used to kill cancerous cells in tumor tissue. There was a significant increase in the size of the EAC on postoperative CT examinations when compared with the preoperative state.

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Oxidative stress parameters and inflammatory and immune mediators as markers of the severity of sepsis. Comparison of three antifungal susceptibility testing methods for the in vitro testing of Candida isolates from patients with HIV infection

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This study is the first to compare human coronary small resistance artery structure from normotensive and hypertensive patients, with and without diabetes undergoing coronary arterial bypass graft surgery. Bryostatins, naturally occurring macrocyclic lactones, have both in vitro and in vivo activity in numerous murine and human tumors. Successful and accurate completion of the replication of damage-containing DNA requires mainly recombination and RAD18-dependent DNA damage tolerance pathways. Finally, the paper concludes with a discussion of the need for a multidisciplinary treatment approach, as well as a call for continued research to further refine existing treatments for these conditions.

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Contacts of culture-confirmed pulmonary TB cases reported to the San Francisco Department of Public Health between 1 March 2005 and 31 December 2007 were included. Identification of potential markers related to neoadjuvant chemotherapy sensitivity of breast cancer by SELDI-TOF MS. calcitrans were not susceptible to the fungal isolates used, regardless of the exposure method. Given the increased prevalence of cardiovascular co morbidities in patients, dermatologists treating psoriasis need to approach the disease as a potentially multisystem disorder and must alert these patients to the potentially negative effects of their disease.

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This article presents the results of a study performed to evaluate 34 variables, constituting the Nursing Stress Scale (NSS) , and their level in the nursing staff of a Rome specialistic hospital. The present study demonstrates that the pharmacokinetics of octreotide in cirrhosis is substantially different from that found in normals. The effect of isoptin on changes in the concentration of potassium in the bodies of patients with hypertension and coronary insufficiency Improving collaboration-communities, health departments, and schools and programs in public health: an academic perspective. Behavior and population structure of Anopheles darlingi in Colombia.

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The amplitude and latency of the elctroretinogram on-response (a- and b-waves) and off-response (d-wave) in addition to eudigox capsule stain the oscillatory potentials of the off-response in normal subjects and patients were compared. Theoretical predictions of trends in spectroscopic properties of homonuclear dimers and volatility of the 7p elements.

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Immunization of mice with recombinant Plasmodium enolase (rPfeno) showed partial protection against malaria. The dopamine transporter (DAT) mediates dopamine uptake in many brain areas and has been suggested to underlie dopamine release in the substantia nigra pars reticulata. Epidemiological study of nocturnal enuresis: analysis of associated factors Answer Our recent large study does show such a brands of clarithromycin in pakistan trend, although the differences are not necessarily clinically significant. However, little is known about the effect of treatment of OSA on brain function, particularly effects on default network processing.

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The endometria of these women were histologically evaluated before therapy was started and again after three months of therapy. These results have been discussed in relation to the positioning of the catalytic and binding sites on these enzymes, the nature of their interaction with actin, their relative stability in cellular situations and the phenomenon of enzyme ambiguity. Wheat samples representing two Canadian wheat classes, CWRS (Canadian Western Red Spring) and CWRW (Canadian Western Red Winter) were used to determine the relationships among F. Systematics and biogeography of Lathyrus (Leguminosae) based on internal transcribed spacer and cpDNA sequence data. Antioxidant potential, cell toxicity, apoptosis induction, and CD44 and CD24 protein expression hershberger gelenk forte plus nebenwirkungen tamoxifen were evaluated after treatment of cells with different concentrations of BCc1 nanocomplex.

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For practical purposes, the in vitro release characteristics of the bioactive metal ions are evaluated as a function of nanoparticle loading density, the chemistry and the texture of the silicone. A study of its effects in patients undergoing myocardial revascularisation. In general, of menopausal related complaints the role of hot flash, atrophic vaginitis and sexual dysfunction is emphasized. Sialic acid bound to glycans in ekspres lonac cena vs lesnar glycolipids and glycoproteins is essential for synaptic plasticity and memory.

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During drug-induced QT-interval prolongation with a large apicobasal and anterolateral dispersion of ventricular repolarization, the Tp-e in the limb leads expresses spatial (total) distribution of repolarization in the whole left ventricle. Nevertheless, controversial sandoz clonazepam 1mg coupons findings exist and estrogen therapy is reported to be related to a higher rate of thromboembolic events and atrial fibrillation in post-menopausal women. The single-nucleotide polymorphism G19A detected in the untranslated exon 1 of leptin gene was not associated with PCOS and does not contribute to elevated levels of leptin. With carp anti-IgGZei sera using the passive hemagglutination inhibition test a paraprotein characterizing determinant (s) is just as well demonstrable as by using a rabbit antiserum. This study examines the associations between alcohol and other drug problems (AOD) and post-traumatic stress disorder (PTSD) symptoms in 499 women recruited from outpatient treatment programs for AOD problems and the general community in western New York.

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Modeling the impacts of the European green crab on commercial shellfisheries. Under control, acetylcholine-treated, and isosorbide dinitrate-treated conditions, cross-sectional areas of sonolucent circle and vessel lumen were measured. All patients were given a test dose of lidocaine after a saline placebo infusion. These results indicate that electrostatic double layer interaction is the primary origin of the observed selectivity. Aim duvanta 20 tablets To understand oral health status of care home residents in Wales using ADHS criteria.