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Detrol (Tolterodine)

Detrol Tablets contain Tolterodine tartrate. The active moiety, Detrol, is a muscarinic receptor antagonist. Tolterodine tartrate is a white, crystalline powder. The pKa value is 9.87 and the solubility in water is 12 mg/mL. It is soluble in methanol, slightly soluble in ethanol, and practically insoluble in toluene. The partition coefficient (Log D) between n-octanol and water is 1.83 at pH 7.3.

Other names for this medication:
Tolterodine, Detrol, Roliten, Detrusitol, Flochek,

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This medication is used to treat an overactive bladder. By relaxing the muscles in the bladder, Detrol improves your ability to control your urination. It helps to reduce leaking of urine, feelings of needing to urinate right away, and frequent trips to the bathroom. This medication belongs to the class of drugs known as antispasmodics.

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In 8 cases bone defects were filled with bone autograft in 3 cases defects were filled with metal augments. In a subsequent electroencephalographic experiment observers were asked to classify contours as objects or non-objects. Laparoscopic endoscopic cooperative surgery as a minimally invasive treatment for gastric submucosal tumor.

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Prevalence of Chlamydia trachomatis in male urethritis in Casablanca Metabolic disposition of primidone and its metabolites in epileptic subjects after single and repeated administration.

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The low number of oocytes collected from the natural ovarian cycles limited the analysis. Differential emotion attribution to neutral faces of own and other races.

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Dry ultrathin sectioning with an oscillating diamond knife was used to produce electron spectroscopic images of mineralized biomineralization foci which were high-pressure frozen and freeze substituted. Focused primarily on Twitter, one of the most commonly used social media tools, the review describes how Twitter is being used in non-psychiatric medical fields and highlights four current and/or potential uses of Twitter in psychiatry: (1) patient care and advocacy, (2) lifelong learning, (3) research data collection and collaboration, and (4) scholarly recognition and impact. Subnormal Estimated Glomerular Filtration Rate Strongly Predict Incident Cardiovascular Events in Type 2 Diabetic Chinese Population With Normoalbuminuria. In addition to providing a unique smoke-flavoring, the smoked, fermented fish material may also impart antioxidant factors thereby extending the shelf life of the product. The relationship of transversus abdominis and lumbar multifidus clinical muscle tests in patients with chronic low back pain.

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The cryopreservation regeneration plant of Gentiana straminea retains very good genetic stability, there is little variation between each plant, so the cryopreservation can be used as a feasible method for resource protection of Gentiana straminea. In the literature, there is a large quantity of various information, results, and hypotheses concerning the late asthmatic response which are, however, often controversial.

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The metacercariae of three trematode species, Paragonimus westermani, Clonorchis sinensis and Metagonimus yokogawai, were collected from the second intermediate hosts: freshwater crabs and fishes, which were obtained using online shopping in Japan, and inoculated to experimental animal rat and dog. In hypertension, structural changes in arteries occur and show differences within and between vascular beds, between species, models and sexes.

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The cloaca acts as a common chamber into which gastrointestinal and urogenital tracts converge in lower vertebrates. A Portuguese sample of 75 young adults with official records of juvenile delinquency in 2010/2011, and 240 young adults from a community sample completed ACE questionnaire and measures of psychosocial adjustment. All the participants in this study were interviewed to collect information on demographic factors and medical history of risk factors and diseases related to hearing loss. The capacity of the EFW percentile to predict Cesarean delivery, Cesarean delivery for non-reassuring fetal status (NRFS), neonatal acidosis and days of neonatal hospitalization was analyzed. CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR-associated) systems are widespread in archaea and bacteria, and research on their molecular mechanisms has led to the development of genome-editing techniques based on a few Type II systems.

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To assess the feasibility and image quality of computed tomography (CT) liver perfusion imaging using an adaptive 4D spiral-mode, developed to extend the z-axis coverage, and to report initial qualitative and quantitative results in patients with cancer metastases. To investigate whether first trimester combined screening for major fetal trisomies is influenced by assisted reproduction techniques from blastocyst transfer, with or without cryopreservation.

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Some theories suggest that repetitive thoughts and behaviours in obsessive compulsive disorder (OCD) are driven by malfunctioning error monitoring. Time-of-flight (ToF) magnetic resonance (MR) angiography was performed using a small animal scanner (9.4 T) equipped with a cryogenic transceive quadrature coil.

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Genetic determinants of on-clopidogrel high platelet reactivity. This is generally a nonsteroid-responsive lesion and for disabling disease, lung transplantation can be a successful option.

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A forebrain-specific loss of Rac1 leads to an SVZ-specific reduction in proliferation, a concomitant increase in cell cycle exit, and premature differentiation. We investigated inbreeding depression at the zygote, seed, and germination stages in the gynomonoecious-gynodioecious Dianthus sylvestris, including pure-sexed plants and a mixed morph. Teratogenicity requires its N-demethylation to dimethadione, the proximate teratogen. Changes in water vapor loss from the skin of metal industry workers monitored during exposure to oils. Analysis of cell cycle phases by flow cytometry showed changes in their proportion and duration, and the expression of the cyclin B1 gene, a marker of entry in mitosis, was decreased, indicating altered cell cycle regulation.

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Subepithelial myofibroblasts are located at the interface between the epithelium and lamina propria in most mucosal tissues. These complexes are present in both rheumatoid and nonrheumatoid SF, with highest levels seen in septic arthritis. Glycaemic Control Impact on Renal Endpoints in Diabetic Patients on Haemodialysis.

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Aortic arch anomalies: simplified classification: surgical experience with ten cases. Changes in pulmonary oxygenation and hemodynamic responses during pulmonary arterial occlusion pressure measurements. In the present paper, after middle pressure chromatograph separation using both positive phase and reversed-phase conditions, the organic additives in ethylene-propylene rubber were identified by infrared spectrometer. The fate of organic micropollutants during long-term/long-distance river bank filtration. Future studies examining guided training in combination with other potentially potent intervention elements may further advise best practices in rehabilitation for individuals with cognitive impairments after acute stroke.

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Is there a role for intravenous acetaminophen in pediatric emergency departments? Leptomeningitis and pachymeningitis are known to occur consecutive to many causes. Bis(2,3-dibromo-4,5-dihydroxybenzyl) ether (BDDE) is a bromophenol compound derived from marine algae. The beta-endorphin-induced secretion of growth hormone but not of prolactin is inhibited by an endogenous opioid antagonist. Our results contribute to defining a link between Msx1 S and AS RNAs resulting in a fine-tuned regulatory loop of Msx1 expression.

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The suitability of the method has been verified by estimating 5-methylcytosine in DNAs of phi X174 and pBR322. Effect of phosphorous on the properties of titania produced from Ti-salt flocculated sludge in water treatment. Data on clinical practice in pediatrics on the use of analgesic, antipyretic, and nonsteroidal anti-inflammatory drugs considering the best available evidence and regulatory-agency approved use are uncertain. In patients with type 2 diabetes mellitus (T2DM), abnormal regulation of glucagon secretion has been implicated in the development of fasting and postprandial hyperglycaemia.

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On-chip assessment of human primary cardiac fibroblasts proliferative responses to uniaxial cyclic mechanical strain. Using the example of unpasteurized or raw milk this paper presents two studies exploring the trust factors associated with online information about the risks and benefits of raw milk consumption.

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We provide a subjective selection and discussion of the most inspiring examples of multifunctional molecular magnets: magnetic sponges, guest-responsive magnets, molecular magnets with ionic conductivity, photomagnets and non-centrosymmetric and chiral magnets. High-risk water, sanitation, and hygiene (WASH) practices are still prevalent in most low-income countries.

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We showed that activins, members of the TGF-beta family growth factors, exist in early amphibian embryos and induce mesoderm tissues and organs in undifferentiated blastomeres (animal cap). Environmental cueing may effect performance on a road test for drivers with dementia of the Alzheimer type. Most patients have other organs involvement by IgG4 related disease.

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Finally, we will briefly discuss studies that have tested the effects of various pharmacologic interventions on biomarkers felt to be relevant to disease pathogenesis. Poisson regression analyses were used to estimate temporal trends in hospital admissions by urban, rural and remote region. Thereafter, throughout the twentieth century, further reports added to our understanding of the neuropathological consequences of a career in boxing, leading to descriptions of a distinct neurodegenerative pathology, termed dementia pugilistica. Impact of Postharvest Nitric Oxide Treatment on Lignin Biosynthesis-Related Genes in Wax Apple (Syzygium samarangense) Fruit. Evaluation of scatter limitation correction: a new method of correcting photopenic artifacts caused by patient motion during whole-body PET/CT imaging.

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Easy to swallow: detection of an extramural jejunal GIST by video capsule endoscopy. Prospective autonomy and critical interests: a narrative defense of the moral authority of advance directives. There was no marked difference in intraoperative flexion and patellar tracking between patients with arthrofibrosis and patients with normal preoperative ROM. Healthy individuals show a delayed reaction to first feeling the illusion (due to latent inhibition), but easily learn the illusion over time.

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Pre-treatment of CRC cells with the antioxidant N-acetylcysteine (NAC) significantly inhibited activation of caspase-4 and altholactone-induced apoptosis. Both mRNA and protein expressions of DPYSL4 were specifically induced by anticancer agents in p53-proficient cells. Secondly, a subline freshly prepared from metastatic lung colonies (F1) displayed a level of surface HS-GAG lower than that of injected B16 cells. We investigated whether Ginkgo biloba extract (EGb761) can provide neuroprotective effects and enhance the efficacy of bone marrow-derived mesenchymal stem cells (BMSCs) in a rat model of experimental autoimmune encephalomyelitis (EAE).

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Mesoporous Pt Nanotubes as a Novel Sensing Platform for Sensitive Detection of Intracellular Hydrogen Peroxide. The remodeling rate of alveolar bone in skeletally immature dogs was greater in the mandible than in the maxilla and remained unaltered between primary and permanent dentitions. There were incisional infections in 3 horses, catheter breakage during removal occurred twice, and in one horse, a catheter was inappropriately placed. The models suitable for the description of the spectra of the probes, both in the rigid limit and in the presence of rotational motions, were developed and successfully applied to model systems.

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Effects on mastitis of overmilking in conjunction with pulsation failure. Apolipoprotein L6, induced in atherosclerotic lesions, promotes apoptosis and blocks Beclin 1-dependent autophagy in atherosclerotic cells. Here we investigated the influence of Shh on thymic epithelial cell (TEC) development.

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This study aimed to measure the magnitude of the preventive effect of safety helmets on clinical outcomes and to compare the effect across different heights of fall. There is a decreasing trend for the use of conservative penile surgery and median centre volumes for penile cancer surgery in NSW are low. Quantitatively controlled in situ formation of hydrogel membranes in microchannels for generation of stable chemical gradients.

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Foodborne pathogens can contaminate raw vegetables at any stage of their production process with a potential for human infection. Possibility of diagnosing pulmonary vascular shunts by rheopneumography Aqueous extract of Lithospermi radix attenuates oxaliplatin-induced neurotoxicity in both in vitro and in vivo models. In 16 patients, T2-weighted MRI was obtained before surgery and STN boundary was demarcated. Results show that local influence and robust methods rank the influence of cases similarly, while the robust method is more objective.

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Morphological analogies of fetal prostate stroma and stromal nodules in BPH. The aim of this article is to present a profile of the national journals in the EPRMJN so as to give a better overview of how the scientific part of PRM in Europe has developed within a national perspective.

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Analysis of two distinct B cell activation pathways mediated by a monoclonal T helper cell. The Chinese hamster genome database ( is an online resource for the Chinese hamster (Cricetulus griseus) and Chinese hamster ovary (CHO) cell communities. Ethnic Minorities and Coronary Heart Disease: an Update and Future Directions.

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Accelerated image reconstruction in fluorescence molecular tomography using a nonuniform updating scheme with momentum and ordered subsets methods. Natural hybridization is increasingly recognized as an important process for the ecology and evolution of natural plant populations and species.

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Neonatal screening for severe combined immunodeficiency caused by an adenosine deaminase defect: a reliable and inexpensive method using tandem mass spectrometry. Here, we used a label-free micro-fluidic platform combined with giant unilamellar lipid vesicles to investigate the permeability of membranes containing mixtures of DOPE and DOPG in DOPC, leading to a label-free measurement of passive membrane-permeability of autofluorescent antibiotics. Competition between relatives and the evolution of dispersal in a parasitoid wasp.

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Portal or bridging fibrosis is an indication for antiviral gemfibrozil simvastatin fda treatment in patients with chronic hepatitis B (CHB). Here we provide evidence that gp120 activates two separate signaling pathways that converge to enhance NMDA-evoked calcium flux by clustering NMDA receptors in modified membrane microdomains. The properties of a novel platelet-activating factor (PAF) antagonist, L-652731, on oedema responses in rabbit skin induced by exogenous inflammatory mediators and by mediators generated endogenously in a reversed passive Arthus reaction have been investigated. Examination of LC in clinically involved skin of patients with scleroderma revealed an absolute or relative decrease in ATPase and OKT6 expression, while staining with anti-DR gave inconclusive results.

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