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Cyclophosphamide
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Cyclophosphamide

Cyclophosphamide is a drug used to treat many types of cancer. It is also used to treat a certain type of kidney disease in children. It is also being studied in the treatment of cancer. Cyclophosphamide damages the cell’s DNA and may kill cancer cells. It may also lower the body’s immune response. Cyclophosphamide is a type of alkylating agent. Also called CTX.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Cyclophosphamide injection is also sometimes used to treat a certain type of lung cancer (small cell lung cancer; SCLC). It is also used to treat rhabdomyosarcoma (a type of cancer of the muscles) and Ewing's sarcoma (a type of bone cancer) in children. Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

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Contrasting the Material Chemistry of Cu2ZnSnSe4 and Cu2ZnSnS(4-x)Se x. Procedures for ERCC1 evaluation varied substantially and included reverse transcriptase quantitative polymerase chain reaction (nine studies), immunohistochemistry (five studies) and other methods (multiple methods-two studies, NER polymorphism-one study). To evaluate the use of abdominal- and thoracic-focused assessment with sonography for trauma (AFAST and TFAST) in nontraumatized dogs and cats in the emergency and critical care setting and to compare prevalence of free fluid identified via these techniques between stable and unstable patients.

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Characterizing industrial catalysts using in situ XAFS under identical conditions. In conjunction with 12 experimentally determined three-dimensional structures of S8 family members, our predicted structures from an archaeon, protozoan and a plant were used for analysis of the catalytic core. To this end, we have estimated and compared various existing independent models, codon models, codon partition models and context-dependent codon partition models for the atpB and rbcL genes of the chloroplast genome, which are frequently used in plant systematics.

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Sandhoff disease gene frequencies in American Jewish and non-Jewish populations. Many people ageing with intellectual disabilities (ID) age in place in group homes. The only effective treatment for ischemic stroke is rapid recanalization of an occluded vessel by dissolving the clot with tissue plasminogen activator (tPA). The results show that imunostaining ability of NIR QDs probes is stronger than that of visible QDs when the two kinds of QDs are simultaneously used to probe the cancer biomarkers such as cytokeratin 20 (CK20) and proliferating cell nuclear antigen (PCNA) in gastric cancer tissues. This study aimed to determine relationships of fear and fatalism with breast cancer screening behavior among Tabriz women in Iran.

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This article describes a project to develop an evidence-based protocol for implementing prenatal vaccination and cocooning in a major medical center in Georgia. The molecular scale is dominated by the constraints imposed by the physico-chemical properties of proteins and their substrates, which give rise to trade-offs and epistatic (non-additive) effects of mutations. Synthesis and characterization of dextran coated magnetite nanoparticles for diagnostics and therapy.

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A case of cancer developing from the vestiges of the thyroglossal canal None of these modalities should be considered for baseline study. In this study, we investigated indoor air quality and symptoms of respiratory illness in 264 nursing workers at 28 day-care centers in Taipei. Oxidative stress was assessed using two markers of protein oxidation, protein carbonyl (PC) and advanced oxidation protein products (AOPP). Selective attention and performance with a multidimensional visual display.

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However, all mutants eventually reached the titre of wild-type virus late post-infection. MMPs are a group of metalloendopeptidases whose major role is in extracellular matrix (ECM) catabolism under physiological and pathological conditions. These data are consistent with the hypothesis that bradycardia during beta-blocker cardiotoxicity is mediated by altered Ca homeostasis. In this paper, we present an inter and intra macro-cell point-dipole model, which can be used to speed-up the determination of dipole-dipole energies at the atomistic level.

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GFAP astrocyte transformation induced uniformly rapid, regionally independent tumor growth, but transformation of GLAST astrocytes induced slowly growing tumors with significant regional bias. Our microsatellite-based linkage analysis shows that intra-specific variation in the distiphallus involves several QTLs of largely additive effect and that a highly significant QTL co-localizes with the same inversion where we have earlier localized a large QTL for a sexually selected courtship song trait. Other studies have shown protein transport of Jacob from synapse-to-nucleus and indicate a role of the protein in neuronal activity-dependent gene expression.

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By using protein arrays we have identified several human PDZ-cellular ligands of this novel domain, one of which is the RIL protein, a known regulator of the cellular tyrosine kinase Src. Our studies identify a new mechanism by which SALL4 represses gene expression through interaction with DNMTs. Acupuncture has been reported to be effective in treating diabetic neuropathy and chemo-induced peripheral neuropathy. This manuscript should be intended as preliminary, exploratory communication, paving the way for further studies.

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Antitumor Effects of Eribulin Mesylate in Gemcitabine-resistant Pancreatic Cancer Cell Lines. Despite the importance of insect-pollination systems, an understanding of those systems is still lacking due to the absence of a genetic analysis of pollen grains that are transported to flowers.

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(1) Although DFP and DIP co-occured in about a quarter of the population, they were not SCs, but rather patient clusters. The results indicated significant differences across the two age groups: adolescents (17-20 year olds) who took more risks on the Stoplight task reported greater frequency and earlier onset of substance use, whereas stoplight performance was not associated with substance use frequency or onset among adults (31-61 year olds).

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The aim of this study is to evaluate the route of seminal vesicle involvement via lymphaticovascular or local extension, as a possible way which may determine the extent of disease as systemic or local. Flies mutant for crq are susceptible to environmental microbes during development and succumb to a variety of microbial infections as adults. To improve knowledge of clinically relevant Islamic teachings regarding end-of-life care. To evaluate the types and incidence of vagus nerve variations and to assess factors related to the vulnerability of vagus nerves during the radiofrequency (RF) ablation of thyroid nodules.

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Our results show that Aurora A plays an important role for facilitating acquisition of BCR-ABL mutation and acquired resistance to tyrosine kinase inhibitors in the culture model and suggest that inhibition of Aurora A may provide an alternative strategy to improve CML treatment to overcome resistance. However, current molecular typing methods only interrogate the antigen recognition site (ARS) of HLA genes, resulting in many cis-trans ambiguities that require additional typing methods to resolve. Comparison of MHC antigen expression on PHA- and MLC-induced T cell lines with that on T and B lymphoblastoid cell lines by cell cycle dependency.

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Interaction mechanism exploration of R-bicalutamide/S-1 with WT/W741L AR using molecular dynamics simulations. Three-dimensional (3-D) facial photographs were taken on all subjects using the 3dMDface system. Successful treatment of carbamazepine poisoning with hemodialysis: a case report and review of the literature. Contrasting Frequencies and Effects of cis- and trans-Regulatory Mutations Affecting Gene Expression. Anaplastic features and BRAF mutation may potentially identify specific subgroups with distinct prognoses.

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To determine the incidence of pectus excavatum (PE) and define anatomical chest wall metrics predictive of elevated mean heart dose (MHD) in patients with left-sided breast cancer receiving adjuvant radiotherapy. Surprisingly, however, empirical evidence for the trade-off is limited. The condition caused substantial visual loss and required high-dose systemic corticosteroid and immunosuppression with methotrexate and ciclosporin to control aggressive intraocular inflammation. We propose as a hypothesis that TR mutations from RCCC and HCC may play tissue-specific roles in carcinogenesis, and that the divergent target gene recognition patterns of TR mutants isolated from the two different types of tumors may arise from different selective pressures during development of RCCC vs. Tubular absorption of albumin was small relative to that of water.

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In summary a new ultrasensitive tool is described for monitoring the molecular dynamics of materials with wide applicability to fundamental and applied science. We investigated the association between FUT2 and FUT3 polymorphisms and UC in Chinese patients.

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Early postnatal docosahexaenoic acid levels and improved preterm brain development. In vitro, whereas acrolein produced a GSH depletion and inhibited B16 cell proliferation, IL-2 increased GSH content and cell proliferation rate compared with untreated cells. Dermal lymphatic invasion was defined radiographically as linear reticulations of the dermis and subcutaneous fat adjacent to the tumor.

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K-ras/COX-2(-/-) mice also had significantly fewer bronchioalveolar hyperplasias than K-ras mice. Reply: Toward Primary Prevention of Asthma: Role of Corticosteroids for the First Rhinovirus Wheeze.

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In this retrospective analysis, we compared the duration of stent patency and frequency of re-interventions in 96 patients diagnosed with unresectable hilar biliary strictures in whom initial 10-mm SEMSs were inserted between June 1999 and November 2008. These findings provide a better understanding of the interactions between hMSCs and collagen biomaterials and suggest a method to manipulate matrix remodeling and deposition of hMSCs, contributing to better scaffolding for tissue engineering and regenerative medicine.

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Three finite element models (FEM) were developed to simulate an endodontic restoration and two typical material tests: diametral tensile test and flexural test. Our findings indicate that dielectric-metal hybrid systems composed of semiconductor NSs and thin metal films act as attractive platforms on which novel nanoscale plasmonic devices can be realized. This post hoc subanalysis shows that MAP0004 was similarly effective in patients whether or not allodynia was present at treatment baseline. Sperm concentration and motility improved post-operatively in all three subgroups, whereas the hemizona index and ultrasonographic measurements improved significantly only in the subgroup that achieved early pregnancies (the mean post-operative percentage of normal morphology was significantly higher), compared to the subgroup without pregnancies.

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Significant progress has been made towards the clinical application of human-machine interfaces (HMIs) based on electromyographic (EMG) pattern recognition for various rehabilitation purposes. Dodecylglycerol induced an efficient stimulation of macrophages for Fc-mediated ingestion whereas tridecylglycerol induced a minimal level of activation. Adult Survivors of Childhood Cancer Have Poor Adherence to Dietary Guidelines.

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Biological activity of peptide and depsipeptide analogs of ophthalmic and norophthalmic acids in glyoxalase I and formaldehyde:NAD-oxidoreductase enzyme systems Inflammatory biomarkers, lung function and an IgE fungal panel to colonising filamentous fungi, yeasts and fungal aeroallergens were measured. Impact of a Diabetes Risk Score on Lifestyle Education and Patient Adherence (IDEA) in Prediabetes: A Multisite Randomized Controlled Trial.

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A novel coronary artery bypass graft design of sequential anastomoses. We examined demographic disparities in parental report of collaborative provider communication and implications for human papillomavirus (HPV) vaccination. A rat model of hereditary RCC, the EKER rat, is associated with a germline mutation of the rat homologue of the tuberous sclerosis gene on human chromosome 16. Abscisic acid (ABA) plays an essential function in plant physiology since it is required for biotic and abiotic stress responses as well as control of plant growth and development. The abnormal fibrinogen polymerized in the presence of calcium and can be further cross-linked by factor XIIIa.

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The purpose of this study was to provide data through the comparative analysis of physical and environmental factors influencing falls in the frail elderly individuals in urban and rural areas, which might be used for developing the fall prevention program. The transformed B cell may still be in need of T-cell help to thrive but simultaneously they may be recognized and destroyed by cytotoxic lymphocytes. Furthermore, disease stage is an important factor impacting outcomes, but these analyses did not stratify patients according to disease stage.

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A monoclonal antibody (MAb), 2H2, against rat synthetic atrial natriuretic factor (ANF) (Arg101-Tyr126) recognizes native ANF related peptides. These articles focused mainly on type of services used and/ or the rate of treatment. Further analyses using microsatellites are planned to confirm these results. A larger amount of Vhs was observed in cells transfected with plasmids expressing vhs from the HIV LTR than from the CMV promoter, consistent with the greater inhibition of HIV replication observed with these constructs.

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The perception of mechanical stimuli in the environment is crucial to the survival of all living organisms. Analysis of effector cells from lung allografts (obtained by bronchoalveolar lavage) revealed the absence of specific cytolytic T lymphocyte (CTL) activity and simvastatin effect on kidneys the presence of a low level of cytolytic activity detected in a lectin-dependent cell-mediated cytotoxicity assay.

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In the auditory forebrain, we identified 121 known miRNAs atorvastatin vs crestor on hdl conserved in other vertebrates. Apart from identifying new pathway deregulation patterns, the tool exploits these patterns by combining different machine learning methods to find clusters of similar samples and build sample classification models.

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This review sets the scene for a collaborative study involving a wide international consortium to investigate, using a standard methodology, the link between ancestry, environment, and ALS phenotype. United States National Health and Nutrition Examination Survey (NHANES) data from 1999 to 2004 and review of existing literature. With improved survival times, FRP retainers could be a viable alternative to metal retainers. Our data indicate that difference between prilosec and generic omeprazole 20mg various lipid indices are not superior to HDL-C levels alone as a clinical tool for estimating LDL particle size.

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